Early D-Aspartate Deficiency Alters Hippocampal Synaptic Plasticity in Juvenile Mice
A recent study shows that embryonic depletion of D-Aspartate in mice leads to enhanced NMDA receptor-dependent synaptic plasticity in the juvenile hippocampus, highlighting its role in brain development.
Lifelong Sulforaphane Intake Shows Promise in Improving Autism-Related Behaviors and Brain Chemistry in Mouse Model
A new study in a mouse model of autism spectrum disorders suggests that lifelong dietary sulforaphane intake may reduce behavioral symptoms and brain inflammation, with differences observed between males and females.
Study Reveals Sex-Specific Behavioral Changes in Mice Lacking α5-Nicotinic Acetylcholine Receptors
A recent study on mice lacking the α5 nicotinic acetylcholine receptor subunit reveals sex-specific behavioral changes relevant to autism and schizophrenia, highlighting differences in anxiety, memory, social interaction, and repetitive behaviors.
Black Mulberry Extract Shows Promise in Reducing Autistic-Like Behaviors in Mouse Model
A study suggests black mulberry extract may reduce autistic-like behaviors in mice by lowering neuroinflammation and oxidative stress, offering a potential avenue for ASD research.
Shank3 Gene Mutation Alters Sleepiness-Related Brain Activity Across Development in Mice
A mutation in the autism-linked gene Shank3 disrupts normal brain responses to sleepiness across development in mice, potentially explaining sleep difficulties in autism.
Dietary Tryptophan Supplementation Shows Promise for Social Behavior in Tuberous Sclerosis Mouse Model
A recent study found that dietary tryptophan supplementation improved social behaviors and reduced anxiety-like symptoms in a mouse model of tuberous sclerosis complex, suggesting nutritional approaches may aid neurodevelopmental disorders.
Study Finds Sex Differences in Brain Cell Death Linked to Autism-Like Behaviors After Prenatal Valproic Acid Exposure
New research shows prenatal valproic acid exposure may cause sex-specific ferroptosis-related brain changes linked to autism-like behaviors in mice, especially affecting males.
Study Finds Altered Striatal Synaptic Plasticity in Autism Model Mice Overexpressing eIF4E
A recent study reveals that mice overexpressing the autism risk gene eIF4E show altered synaptic plasticity in the striatum, potentially contributing to ASD-related behaviors.
Mouse Model with Pten Mutation Shows Changes in Social Behavior and Brain Activity
A mouse model with a germline Pten mutation shows social behavior impairments, microglial activation, and increased oxytocin activity, shedding light on neurodevelopmental disorder mechanisms.
Astrocytes in the Hippocampus Influence Inhibitory Circuit Development and Behavior in Fragile X Syndrome Mouse Model
Research in a Fragile X Syndrome mouse model reveals that astrocytes in the hippocampus influence inhibitory synapse development and behaviors related to socialization and spatial memory, highlighting new avenues for understanding and potentially…