Shank3 Gene Mutation Alters Sleepiness-Related Brain Activity Across Development in Mice
A mutation in the autism-linked gene Shank3 disrupts normal brain responses to sleepiness across development in mice, potentially explaining sleep difficulties in autism.
Study Finds Sex Differences in Brain Cell Death Linked to Autism-Like Behaviors After Prenatal Valproic Acid Exposure
New research shows prenatal valproic acid exposure may cause sex-specific ferroptosis-related brain changes linked to autism-like behaviors in mice, especially affecting males.
Prenatal Valproate Exposure in Rats Shows Sex-Specific Behavioral and Brain Excitability Changes Linked to Autism Traits
A new study using a rat model of prenatal valproate exposure reveals sex-specific differences in brain excitability and social behavior linked to autism traits, with males showing more social deficits and physical markers correlating with neural changes.
Prenatal Heat Exposure and Neurodevelopment: Exploring the Placenta-Brain Connection
A systematic review highlights potential links between prenatal heat exposure, placental inflammation, and neurodevelopmental outcomes, emphasizing the need for further research.
CACNA1C Genetic Variants Influence Neuronal Networks Through Distinct Mechanisms
New research reveals that different genetic variants in CACNA1C affect neuronal networks and development through distinct pathways, influencing conditions like autism and epilepsy.
Study Highlights General Cognitive Factors Over Statistical Learning in Predicting Language Skills Across Developmental Profiles
A study of Hungarian children reveals that verbal working memory and perceptual speed better predict language skills than statistical learning, across typical and neurodevelopmental conditions.
RORA Gene’s Role in Autism Spectrum Disorder Highlights Sex-Specific Biological Pathways
New research highlights the RORA gene's role in autism spectrum disorder, revealing sex-specific influences that may explain male-biased risk and female protection.
New Insights Into Neuroglial Changes in Autism from Preclinical Research
A recent correction in preclinical research sheds light on neuroglial changes in autism, emphasizing the complex role of brain support cells in ASD.
Prenatal Environmental Factors Linked to Epigenetic Changes in Brain Aromatase Gene
A study of 906 newborns found that prenatal exposure to chemicals like bisphenol A, reduced sunlight, and air pollution may increase DNA methylation of the brain aromatase gene, potentially affecting neurodevelopment.
New Research Highlights Sex Differences in Genetic Prediction of Autism Spectrum Disorder
A new study reveals that genetic predictors of autism spectrum disorder differ between males and females, highlighting the importance of sex-specific approaches in ASD risk assessment.