Study Finds Autism-Linked Genetic Variants Cluster into Two Molecular Patterns in Mouse Brains
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A study of 17 autism mouse models reveals that diverse genetic variants cluster into two opposing molecular states, suggesting shared biological pathways in autism.
Shank3 Gene Mutation Alters Sleepiness-Related Brain Activity Across Development in Mice
A mutation in the autism-linked gene Shank3 disrupts normal brain responses to sleepiness across development in mice, potentially explaining sleep difficulties in autism.
Gene Activity During Brain Development Influenced by Nuclear Positioning
Research on developing human brain tissue suggests that gene activation increases when genes move from the nucleus edge toward RNA-processing regions, highlighting nuclear positioning's role in brain development.